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alendronate (a LEN droe nate)

What is the most important information I should know about Fosamax?
• Some forms of alendronate are taken once a day find information fosamax. Others are taken onlyonce a week find information fosamax. It is very important that you follow your doctor's directions find information fosamax. If you take alendronate once a week, take it on the same day each week find information fosamax.
• After swallowing the tablet, do not lie down, remain fully upright sitting,standing or walking, for at least 30 minutes and until after you have eaten find information fosamax.
• Do not crush, chew, or suck the tablets find information fosamax. Swallow them whole find information fosamax.
• Do not take alendronate at bedtime or before getting up for the day find information fosamax.


What is alendronate?
• Alendronate is a compound that alters the cycle of bone formation andbreakdown in your body find information fosamax. alendronate increases new bone formation find information fosamax.
• Fosamax is used to treat and prevent osteoporosis and to treat Paget'sdisease find information fosamax. Fosamax is also used to treat osteoporosis that is caused by treatmentwith a corticosteroid find information fosamax.
• Fosamax may also be used for purposes other than those listed in thismedication guide find information fosamax.


Who should not take Fosamax?
• Before taking Fosamax, tell your doctor if you
· have a problem swallowing, such as a narrowing of your esophagus;
· have esophageal ulcers or an esophageal disease;
· have a condition that causes low levels of calcium in your body;
· have kidney disease;
· have stomach ulcers or other stomach or digestive problems; or
· are unable to stand or sit upright for at least 30 minutes find information fosamax.
• You may not be able to take Fosamax, or you may require a lower doseor special monitoring during treatment if you have any of the conditions listedabove find information fosamax.
• Fosamax is in the FDA pregnancy category C find information fosamax. This means that it is notknown whether Fosamax will harm an unborn baby find information fosamax. Do not take Fosamax withoutfirst talking to your doctor if you are pregnant find information fosamax.
• It is also not known whether Fosamax passes into breast milk find information fosamax. Do nottake Fosamax without first talking to your doctor if you are breast-feedinga baby find information fosamax.


How should I take Fosamax?
• Take Fosamax exactly as directed by your doctor find information fosamax. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you find information fosamax.
• Some forms of alendronate are taken once a day find information fosamax. Others are taken onlyonce a week find information fosamax. It is very important that you follow your doctor's directions find information fosamax. If you take alendronate once a week, take it on the same day each week find information fosamax.
• Take Fosamax first thing in the morning, at least 30 minutes before youeat any food or drink any liquid (other than plain water) find information fosamax. This timing is veryimportant for getting the maximum amount of medication from each dose find information fosamax. Foodsand beverages greatly decrease the effect of Fosamax find information fosamax.
• Take each dose with a full glass (6 to 8 ounces) of tap water or bottledwater find information fosamax. Taking each dose with a full glass of water will ensure proper swallowingof the tablet and reduce the risk of mouth or throat irritation find information fosamax. Do not takethis medication with mineral water, juice, or any other beverage find information fosamax.
• After swallowing the tablet, do not lie down, remain fully upright sitting,standing or walking, for at least 30 minutes and until after you have eaten find information fosamax.
• Do not crush, chew, or suck the tablets find information fosamax. Swallow them whole find information fosamax.
• Do not take Fosamax at bedtime or before getting up for the day find information fosamax.
• If you have difficulty or pain upon swallowing, chest pain, or new orworsening heartburn, stop taking Fosamax and call your doctor find information fosamax.
• It is important that you continue taking Fosamax for as long as yourdoctor prescribes it find information fosamax. Fosamax can treat or prevent osteoporosis only if youcontinue to take it find information fosamax.
• Store Fosamax at room temperature away from moisture and heat find information fosamax.


What happens if I miss a dose?
• If you take alendronate every day and you miss a dose, skip that doseand take your next regularly scheduled dose the following day find information fosamax. Missing one dosewill not affect your treatment find information fosamax. Do not take two tablets at the same time find information fosamax.
• If you take alendronate once a week and you miss a dose, take the misseddose on the morning after you remember find information fosamax. Do not take two tablets on the sameday find information fosamax. Return to taking one tablet once a week, as originally scheduled on yourchosen day find information fosamax.


What happens if I overdose?
• Seek emergency medical attention find information fosamax.
• The symptoms of an Fosamax overdose are unknown, but the following symptomsmight be expected: nausea, heartburn, pain in your abdomen, other stomach-relatedsymptoms, muscle cramps, uncontrollable facial grimacing, seizures, irritability,and abnormal behavior find information fosamax.


What should I avoid while taking Fosamax?
• Follow you doctor's recommendations about drinking alcohol and smoking find information fosamax. These activities are related to decreased bone density find information fosamax.


What are the possible side effects of Fosamax?
• Stop taking Fosamax and seek emergency medical attention or contact yourdoctor immediately if you experience any of the following serious side effects:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· difficulty or pain when swallowing;
· chest pain;
· pain or burning under your ribs or in your back; or
· new or worsening heartburn find information fosamax.
• Other, less serious side effects may be more likely to occur find information fosamax. Continueto take Fosamax and talk to your doctor if you experience
· abdominal discomfort;
· stomach upset, nausea, vomiting, diarrhea, or constipation;
· headache;
· muscle, bone, or joint soreness or aches;
· eye pain;
· a rash; or
· an altered sense of taste find information fosamax.
• Side effects other than those listed here may also occur find information fosamax. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome find information fosamax.


What other drugs will affect Fosamax?
• Antacids and other medicines taken by mouth may decrease the effectsof Fosamax find information fosamax. Do not take any other medicines within 30 minutes after a dose ofFosamax find information fosamax. Talk to your doctor before taking any other medicines during treatmentwith Fosamax find information fosamax.
• Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen(Motrin, Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin(Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro),nabumetone (Relafen), piroxicam (Feldene), and others may increase the riskof damage to your stomach if they are taken during treatment with Fosamax find information fosamax. Talkto your doctor before taking anti-inflammatory medications, pain relievers orfever reducers during treatment with Fosamax find information fosamax.
• Drugs other than those listed here may also interact with Fosamax find information fosamax. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines find information fosamax.


Where can I get more information?
• Your pharmacist has more information about Fosamax written for healthprofessionals that you may read find information fosamax.


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