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fosamax renal insufficiency
alendronate (a LEN droe nate)

What is the most important information I should know about Fosamax?
• Some forms of alendronate are taken once a day fosamax renal insufficiency. Others are taken onlyonce a week fosamax renal insufficiency. It is very important that you follow your doctor's directions fosamax renal insufficiency. If you take alendronate once a week, take it on the same day each week fosamax renal insufficiency.
• After swallowing the tablet, do not lie down, remain fully upright sitting,standing or walking, for at least 30 minutes and until after you have eaten fosamax renal insufficiency.
• Do not crush, chew, or suck the tablets fosamax renal insufficiency. Swallow them whole fosamax renal insufficiency.
• Do not take alendronate at bedtime or before getting up for the day fosamax renal insufficiency.


What is alendronate?
• Alendronate is a compound that alters the cycle of bone formation andbreakdown in your body fosamax renal insufficiency. alendronate increases new bone formation fosamax renal insufficiency.
• Fosamax is used to treat and prevent osteoporosis and to treat Paget'sdisease fosamax renal insufficiency. Fosamax is also used to treat osteoporosis that is caused by treatmentwith a corticosteroid fosamax renal insufficiency.
• Fosamax may also be used for purposes other than those listed in thismedication guide fosamax renal insufficiency.


Who should not take Fosamax?
• Before taking Fosamax, tell your doctor if you
· have a problem swallowing, such as a narrowing of your esophagus;
· have esophageal ulcers or an esophageal disease;
· have a condition that causes low levels of calcium in your body;
· have kidney disease;
· have stomach ulcers or other stomach or digestive problems; or
· are unable to stand or sit upright for at least 30 minutes fosamax renal insufficiency.
• You may not be able to take Fosamax, or you may require a lower doseor special monitoring during treatment if you have any of the conditions listedabove fosamax renal insufficiency.
• Fosamax is in the FDA pregnancy category C fosamax renal insufficiency. This means that it is notknown whether Fosamax will harm an unborn baby fosamax renal insufficiency. Do not take Fosamax withoutfirst talking to your doctor if you are pregnant fosamax renal insufficiency.
• It is also not known whether Fosamax passes into breast milk fosamax renal insufficiency. Do nottake Fosamax without first talking to your doctor if you are breast-feedinga baby fosamax renal insufficiency.


How should I take Fosamax?
• Take Fosamax exactly as directed by your doctor fosamax renal insufficiency. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you fosamax renal insufficiency.
• Some forms of alendronate are taken once a day fosamax renal insufficiency. Others are taken onlyonce a week fosamax renal insufficiency. It is very important that you follow your doctor's directions fosamax renal insufficiency. If you take alendronate once a week, take it on the same day each week fosamax renal insufficiency.
• Take Fosamax first thing in the morning, at least 30 minutes before youeat any food or drink any liquid (other than plain water) fosamax renal insufficiency. This timing is veryimportant for getting the maximum amount of medication from each dose fosamax renal insufficiency. Foodsand beverages greatly decrease the effect of Fosamax fosamax renal insufficiency.
• Take each dose with a full glass (6 to 8 ounces) of tap water or bottledwater fosamax renal insufficiency. Taking each dose with a full glass of water will ensure proper swallowingof the tablet and reduce the risk of mouth or throat irritation fosamax renal insufficiency. Do not takethis medication with mineral water, juice, or any other beverage fosamax renal insufficiency.
• After swallowing the tablet, do not lie down, remain fully upright sitting,standing or walking, for at least 30 minutes and until after you have eaten fosamax renal insufficiency.
• Do not crush, chew, or suck the tablets fosamax renal insufficiency. Swallow them whole fosamax renal insufficiency.
• Do not take Fosamax at bedtime or before getting up for the day fosamax renal insufficiency.
• If you have difficulty or pain upon swallowing, chest pain, or new orworsening heartburn, stop taking Fosamax and call your doctor fosamax renal insufficiency.
• It is important that you continue taking Fosamax for as long as yourdoctor prescribes it fosamax renal insufficiency. Fosamax can treat or prevent osteoporosis only if youcontinue to take it fosamax renal insufficiency.
• Store Fosamax at room temperature away from moisture and heat fosamax renal insufficiency.


What happens if I miss a dose?
• If you take alendronate every day and you miss a dose, skip that doseand take your next regularly scheduled dose the following day fosamax renal insufficiency. Missing one dosewill not affect your treatment fosamax renal insufficiency. Do not take two tablets at the same time fosamax renal insufficiency.
• If you take alendronate once a week and you miss a dose, take the misseddose on the morning after you remember fosamax renal insufficiency. Do not take two tablets on the sameday fosamax renal insufficiency. Return to taking one tablet once a week, as originally scheduled on yourchosen day fosamax renal insufficiency.


What happens if I overdose?
• Seek emergency medical attention fosamax renal insufficiency.
• The symptoms of an Fosamax overdose are unknown, but the following symptomsmight be expected: nausea, heartburn, pain in your abdomen, other stomach-relatedsymptoms, muscle cramps, uncontrollable facial grimacing, seizures, irritability,and abnormal behavior fosamax renal insufficiency.


What should I avoid while taking Fosamax?
• Follow you doctor's recommendations about drinking alcohol and smoking fosamax renal insufficiency. These activities are related to decreased bone density fosamax renal insufficiency.


What are the possible side effects of Fosamax?
• Stop taking Fosamax and seek emergency medical attention or contact yourdoctor immediately if you experience any of the following serious side effects:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· difficulty or pain when swallowing;
· chest pain;
· pain or burning under your ribs or in your back; or
· new or worsening heartburn fosamax renal insufficiency.
• Other, less serious side effects may be more likely to occur fosamax renal insufficiency. Continueto take Fosamax and talk to your doctor if you experience
· abdominal discomfort;
· stomach upset, nausea, vomiting, diarrhea, or constipation;
· headache;
· muscle, bone, or joint soreness or aches;
· eye pain;
· a rash; or
· an altered sense of taste fosamax renal insufficiency.
• Side effects other than those listed here may also occur fosamax renal insufficiency. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome fosamax renal insufficiency.


What other drugs will affect Fosamax?
• Antacids and other medicines taken by mouth may decrease the effectsof Fosamax fosamax renal insufficiency. Do not take any other medicines within 30 minutes after a dose ofFosamax fosamax renal insufficiency. Talk to your doctor before taking any other medicines during treatmentwith Fosamax fosamax renal insufficiency.
• Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen(Motrin, Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin(Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro),nabumetone (Relafen), piroxicam (Feldene), and others may increase the riskof damage to your stomach if they are taken during treatment with Fosamax fosamax renal insufficiency. Talkto your doctor before taking anti-inflammatory medications, pain relievers orfever reducers during treatment with Fosamax fosamax renal insufficiency.
• Drugs other than those listed here may also interact with Fosamax fosamax renal insufficiency. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines fosamax renal insufficiency.


Where can I get more information?
• Your pharmacist has more information about Fosamax written for healthprofessionals that you may read fosamax renal insufficiency.


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