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side effects of fosamax infusion
alendronate (a LEN droe nate)

What is the most important information I should know about Fosamax?
• Some forms of alendronate are taken once a day side effects of fosamax infusion. Others are taken onlyonce a week side effects of fosamax infusion. It is very important that you follow your doctor's directions side effects of fosamax infusion. If you take alendronate once a week, take it on the same day each week side effects of fosamax infusion.
• After swallowing the tablet, do not lie down, remain fully upright sitting,standing or walking, for at least 30 minutes and until after you have eaten side effects of fosamax infusion.
• Do not crush, chew, or suck the tablets side effects of fosamax infusion. Swallow them whole side effects of fosamax infusion.
• Do not take alendronate at bedtime or before getting up for the day side effects of fosamax infusion.


What is alendronate?
• Alendronate is a compound that alters the cycle of bone formation andbreakdown in your body side effects of fosamax infusion. alendronate increases new bone formation side effects of fosamax infusion.
• Fosamax is used to treat and prevent osteoporosis and to treat Paget'sdisease side effects of fosamax infusion. Fosamax is also used to treat osteoporosis that is caused by treatmentwith a corticosteroid side effects of fosamax infusion.
• Fosamax may also be used for purposes other than those listed in thismedication guide side effects of fosamax infusion.


Who should not take Fosamax?
• Before taking Fosamax, tell your doctor if you
· have a problem swallowing, such as a narrowing of your esophagus;
· have esophageal ulcers or an esophageal disease;
· have a condition that causes low levels of calcium in your body;
· have kidney disease;
· have stomach ulcers or other stomach or digestive problems; or
· are unable to stand or sit upright for at least 30 minutes side effects of fosamax infusion.
• You may not be able to take Fosamax, or you may require a lower doseor special monitoring during treatment if you have any of the conditions listedabove side effects of fosamax infusion.
• Fosamax is in the FDA pregnancy category C side effects of fosamax infusion. This means that it is notknown whether Fosamax will harm an unborn baby side effects of fosamax infusion. Do not take Fosamax withoutfirst talking to your doctor if you are pregnant side effects of fosamax infusion.
• It is also not known whether Fosamax passes into breast milk side effects of fosamax infusion. Do nottake Fosamax without first talking to your doctor if you are breast-feedinga baby side effects of fosamax infusion.


How should I take Fosamax?
• Take Fosamax exactly as directed by your doctor side effects of fosamax infusion. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you side effects of fosamax infusion.
• Some forms of alendronate are taken once a day side effects of fosamax infusion. Others are taken onlyonce a week side effects of fosamax infusion. It is very important that you follow your doctor's directions side effects of fosamax infusion. If you take alendronate once a week, take it on the same day each week side effects of fosamax infusion.
• Take Fosamax first thing in the morning, at least 30 minutes before youeat any food or drink any liquid (other than plain water) side effects of fosamax infusion. This timing is veryimportant for getting the maximum amount of medication from each dose side effects of fosamax infusion. Foodsand beverages greatly decrease the effect of Fosamax side effects of fosamax infusion.
• Take each dose with a full glass (6 to 8 ounces) of tap water or bottledwater side effects of fosamax infusion. Taking each dose with a full glass of water will ensure proper swallowingof the tablet and reduce the risk of mouth or throat irritation side effects of fosamax infusion. Do not takethis medication with mineral water, juice, or any other beverage side effects of fosamax infusion.
• After swallowing the tablet, do not lie down, remain fully upright sitting,standing or walking, for at least 30 minutes and until after you have eaten side effects of fosamax infusion.
• Do not crush, chew, or suck the tablets side effects of fosamax infusion. Swallow them whole side effects of fosamax infusion.
• Do not take Fosamax at bedtime or before getting up for the day side effects of fosamax infusion.
• If you have difficulty or pain upon swallowing, chest pain, or new orworsening heartburn, stop taking Fosamax and call your doctor side effects of fosamax infusion.
• It is important that you continue taking Fosamax for as long as yourdoctor prescribes it side effects of fosamax infusion. Fosamax can treat or prevent osteoporosis only if youcontinue to take it side effects of fosamax infusion.
• Store Fosamax at room temperature away from moisture and heat side effects of fosamax infusion.


What happens if I miss a dose?
• If you take alendronate every day and you miss a dose, skip that doseand take your next regularly scheduled dose the following day side effects of fosamax infusion. Missing one dosewill not affect your treatment side effects of fosamax infusion. Do not take two tablets at the same time side effects of fosamax infusion.
• If you take alendronate once a week and you miss a dose, take the misseddose on the morning after you remember side effects of fosamax infusion. Do not take two tablets on the sameday side effects of fosamax infusion. Return to taking one tablet once a week, as originally scheduled on yourchosen day side effects of fosamax infusion.


What happens if I overdose?
• Seek emergency medical attention side effects of fosamax infusion.
• The symptoms of an Fosamax overdose are unknown, but the following symptomsmight be expected: nausea, heartburn, pain in your abdomen, other stomach-relatedsymptoms, muscle cramps, uncontrollable facial grimacing, seizures, irritability,and abnormal behavior side effects of fosamax infusion.


What should I avoid while taking Fosamax?
• Follow you doctor's recommendations about drinking alcohol and smoking side effects of fosamax infusion. These activities are related to decreased bone density side effects of fosamax infusion.


What are the possible side effects of Fosamax?
• Stop taking Fosamax and seek emergency medical attention or contact yourdoctor immediately if you experience any of the following serious side effects:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· difficulty or pain when swallowing;
· chest pain;
· pain or burning under your ribs or in your back; or
· new or worsening heartburn side effects of fosamax infusion.
• Other, less serious side effects may be more likely to occur side effects of fosamax infusion. Continueto take Fosamax and talk to your doctor if you experience
· abdominal discomfort;
· stomach upset, nausea, vomiting, diarrhea, or constipation;
· headache;
· muscle, bone, or joint soreness or aches;
· eye pain;
· a rash; or
· an altered sense of taste side effects of fosamax infusion.
• Side effects other than those listed here may also occur side effects of fosamax infusion. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome side effects of fosamax infusion.


What other drugs will affect Fosamax?
• Antacids and other medicines taken by mouth may decrease the effectsof Fosamax side effects of fosamax infusion. Do not take any other medicines within 30 minutes after a dose ofFosamax side effects of fosamax infusion. Talk to your doctor before taking any other medicines during treatmentwith Fosamax side effects of fosamax infusion.
• Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen(Motrin, Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin(Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro),nabumetone (Relafen), piroxicam (Feldene), and others may increase the riskof damage to your stomach if they are taken during treatment with Fosamax side effects of fosamax infusion. Talkto your doctor before taking anti-inflammatory medications, pain relievers orfever reducers during treatment with Fosamax side effects of fosamax infusion.
• Drugs other than those listed here may also interact with Fosamax side effects of fosamax infusion. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines side effects of fosamax infusion.


Where can I get more information?
• Your pharmacist has more information about Fosamax written for healthprofessionals that you may read side effects of fosamax infusion.


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