synthroid and fosamax interaction

What is the most important information I should know about Fosamax?
• Some forms of alendronate are taken once a day synthroid and fosamax interaction. Others are taken onlyonce a week synthroid and fosamax interaction. It is very important that you follow your doctor's directions synthroid and fosamax interaction. If you take alendronate once a week, take it on the same day each week synthroid and fosamax interaction.
• After swallowing the tablet, do not lie down, remain fully upright sitting,standing or walking, for at least 30 minutes and until after you have eaten synthroid and fosamax interaction.
• Do not crush, chew, or suck the tablets synthroid and fosamax interaction. Swallow them whole synthroid and fosamax interaction.
• Do not take alendronate at bedtime or before getting up for the day synthroid and fosamax interaction.

What is alendronate?
• Alendronate is a compound that alters the cycle of bone formation andbreakdown in your body synthroid and fosamax interaction. alendronate increases new bone formation synthroid and fosamax interaction.
• Fosamax is used to treat and prevent osteoporosis and to treat Paget'sdisease synthroid and fosamax interaction. Fosamax is also used to treat osteoporosis that is caused by treatmentwith a corticosteroid synthroid and fosamax interaction.
• Fosamax may also be used for purposes other than those listed in thismedication guide synthroid and fosamax interaction.

Who should not take Fosamax?
• Before taking Fosamax, tell your doctor if you
· have a problem swallowing, such as a narrowing of your esophagus;
· have esophageal ulcers or an esophageal disease;
· have a condition that causes low levels of calcium in your body;
· have kidney disease;
· have stomach ulcers or other stomach or digestive problems; or
· are unable to stand or sit upright for at least 30 minutes synthroid and fosamax interaction.
• You may not be able to take Fosamax, or you may require a lower doseor special monitoring during treatment if you have any of the conditions listedabove synthroid and fosamax interaction.
• Fosamax is in the FDA pregnancy category C synthroid and fosamax interaction. This means that it is notknown whether Fosamax will harm an unborn baby synthroid and fosamax interaction. Do not take Fosamax withoutfirst talking to your doctor if you are pregnant synthroid and fosamax interaction.
• It is also not known whether Fosamax passes into breast milk synthroid and fosamax interaction. Do nottake Fosamax without first talking to your doctor if you are breast-feedinga baby synthroid and fosamax interaction.

How should I take Fosamax?
• Take Fosamax exactly as directed by your doctor synthroid and fosamax interaction. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you synthroid and fosamax interaction.
• Some forms of alendronate are taken once a day synthroid and fosamax interaction. Others are taken onlyonce a week synthroid and fosamax interaction. It is very important that you follow your doctor's directions synthroid and fosamax interaction. If you take alendronate once a week, take it on the same day each week synthroid and fosamax interaction.
• Take Fosamax first thing in the morning, at least 30 minutes before youeat any food or drink any liquid (other than plain water) synthroid and fosamax interaction. This timing is veryimportant for getting the maximum amount of medication from each dose synthroid and fosamax interaction. Foodsand beverages greatly decrease the effect of Fosamax synthroid and fosamax interaction.
• Take each dose with a full glass (6 to 8 ounces) of tap water or bottledwater synthroid and fosamax interaction. Taking each dose with a full glass of water will ensure proper swallowingof the tablet and reduce the risk of mouth or throat irritation synthroid and fosamax interaction. Do not takethis medication with mineral water, juice, or any other beverage synthroid and fosamax interaction.
• After swallowing the tablet, do not lie down, remain fully upright sitting,standing or walking, for at least 30 minutes and until after you have eaten synthroid and fosamax interaction.
• Do not crush, chew, or suck the tablets synthroid and fosamax interaction. Swallow them whole synthroid and fosamax interaction.
• Do not take Fosamax at bedtime or before getting up for the day synthroid and fosamax interaction.
• If you have difficulty or pain upon swallowing, chest pain, or new orworsening heartburn, stop taking Fosamax and call your doctor synthroid and fosamax interaction.
• It is important that you continue taking Fosamax for as long as yourdoctor prescribes it synthroid and fosamax interaction. Fosamax can treat or prevent osteoporosis only if youcontinue to take it synthroid and fosamax interaction.
• Store Fosamax at room temperature away from moisture and heat synthroid and fosamax interaction.

What happens if I miss a dose?
• If you take alendronate every day and you miss a dose, skip that doseand take your next regularly scheduled dose the following day synthroid and fosamax interaction. Missing one dosewill not affect your treatment synthroid and fosamax interaction. Do not take two tablets at the same time synthroid and fosamax interaction.
• If you take alendronate once a week and you miss a dose, take the misseddose on the morning after you remember synthroid and fosamax interaction. Do not take two tablets on the sameday synthroid and fosamax interaction. Return to taking one tablet once a week, as originally scheduled on yourchosen day synthroid and fosamax interaction.

What happens if I overdose?
• Seek emergency medical attention synthroid and fosamax interaction.
• The symptoms of an Fosamax overdose are unknown, but the following symptomsmight be expected: nausea, heartburn, pain in your abdomen, other stomach-relatedsymptoms, muscle cramps, uncontrollable facial grimacing, seizures, irritability,and abnormal behavior synthroid and fosamax interaction.

What should I avoid while taking Fosamax?
• Follow you doctor's recommendations about drinking alcohol and smoking synthroid and fosamax interaction. These activities are related to decreased bone density synthroid and fosamax interaction.

What are the possible side effects of Fosamax?
• Stop taking Fosamax and seek emergency medical attention or contact yourdoctor immediately if you experience any of the following serious side effects:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· difficulty or pain when swallowing;
· chest pain;
· pain or burning under your ribs or in your back; or
· new or worsening heartburn synthroid and fosamax interaction.
• Other, less serious side effects may be more likely to occur synthroid and fosamax interaction. Continueto take Fosamax and talk to your doctor if you experience
· abdominal discomfort;
· stomach upset, nausea, vomiting, diarrhea, or constipation;
· headache;
· muscle, bone, or joint soreness or aches;
· eye pain;
· a rash; or
· an altered sense of taste synthroid and fosamax interaction.
• Side effects other than those listed here may also occur synthroid and fosamax interaction. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome synthroid and fosamax interaction.

What other drugs will affect Fosamax?
• Antacids and other medicines taken by mouth may decrease the effectsof Fosamax synthroid and fosamax interaction. Do not take any other medicines within 30 minutes after a dose ofFosamax synthroid and fosamax interaction. Talk to your doctor before taking any other medicines during treatmentwith Fosamax synthroid and fosamax interaction.
• Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen(Motrin, Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin(Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro),nabumetone (Relafen), piroxicam (Feldene), and others may increase the riskof damage to your stomach if they are taken during treatment with Fosamax synthroid and fosamax interaction. Talkto your doctor before taking anti-inflammatory medications, pain relievers orfever reducers during treatment with Fosamax synthroid and fosamax interaction.
• Drugs other than those listed here may also interact with Fosamax synthroid and fosamax interaction. Talkto your doctor and pharmacist before taking any prescription or over-the-countermedicines synthroid and fosamax interaction.

Where can I get more information?
• Your pharmacist has more information about Fosamax written for healthprofessionals that you may read synthroid and fosamax interaction.

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